Premammillary dorsal hypothalamus nucleus

Nucleus premammillaris dorsalis

Hypothalamic nucleus, dorsal premammillary., PMD

The nucleus receives signals from, among other things, the bed core of the streak and the septal region. It is further connected to the PAG and the ventral tegment nucleus and connected to the local network of the hypothalamus.

In rats, the PMD nucleus appears to be crucial for adequate behaviour in relation to external threats; i.e. immobility, planning of escape route and escape. Here, the connection with the ventral tegment nucleus (spatial/spatial working memory) probably plays a major role when it comes to exploiting the escape possibilities of the surroundings.

Comoli E, Ribeiro-Barbosa ER, Canteras NS. (2000) Afferent connections of the dorsal premammillary nucleus. J Comp Neurol; 423(1):83-98.