Premammillary ventral hypothalamus nucleus

Nucleus premammillaris ventralis

Hypothalamus nucleus, ventral premammillary, VPM, hypothalamus

The core, one on hay. and one on the left. side, located posteriorly in the inner hypothalamus zone.

The nucleus has round-trip traffic with, among other things, the bed nucleus of the end streak, the amygdala and the septal region and is connected to the local network of the hypothalamus.

In rats, the PMV nucleus appears to be crucial for adequate social behaviour. If the core is damaged, the animal develops an offensive aggressiveness.
The nucleus is also believed to participate in the coordination of energy metabolism with the reproductive cycle; This under the influence of the hormone leptin.

Donato Jr. J, et al. (2009) The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion. J. Neurosci., 29(16): 5240-5250.