Outer preopticus nucleus

Nucleus preopticus lateralis

Hypothalamus nucleus, lateral preopticus

The core, located one left. and a t.hay. In area preoptica, is active during non-REM sleep (deep sleep) and slows down nerve cells with awakening effect.

Experiments on mice suggest that some anesthetics have their soporific effect precisely by activating neurons in the outer preopticus nucleus.

Shadan, S. Sleep to oblivion. Nature 491, 46 (2012)