Median eminence

Eminentia mediana hypothalami

Small elevation posterior of tuber cinereum adjacent to pituitary stalk. The eminent mediana is the starting area of the hypothalamic-pituitary portal system that connects the hypothalamus to the frontal lobe of the pituitary gland.

Various pituitary-controlling (pituitary-tropic) hormones are formed by nerve cells in the hypothalamus. The control hormones are transported axonally to the eminentite mediana where they are released and taken up by the blood in the portal system and then delivered "down" to the capillaries in the frontal lobe of the pituitary gland. Here, the control hormones leave the bloodstream and can affect their various target cells.

Pituitary hormones include:
Corticotropin Releasing Factor, CRF.
Gonadotropin Releasing Hormone, GnRH.
Thyrotropin Releasing Hormone, TRH.
Growth Hormone Releasing Hormone, GHRH.
Dopamine, DA, from cell group A12 of the nucleus arcuatus/infundibularis.

Eminentia mediana lacks a blood-brain barrier and is counted among the circumventricular organs.

Not to be confused with "Eminentia medialis".