The nucleus intermediomedialis receives and processes visceralafferent information from the entire spinal cord as well as afference from PAG and the caudal group of nuclei (serotonin!). The nucleus intermediomedialis builds autonomic reflex arcs via transverse connections with the adjacent nucleus intermediolateralis and the sacral parasympathetic nuclei, which in turn generate the preganglionic signal outflow from the spinal cord.
The nucleus intermediomedialis develops together with the nucleus intermediolateralis and the sacral parasympathetic nuclei of the embryonic spinal cord from a single longitudinal strand of immature neurons, such a strand of cells to hay. and one to the left. The neural cord eventually splits into two distinct neuronal columns, a more powerful external/lateral – the prospective nucleus intermediolateralis and the sacral parasympathetic nuclei – and a thinner inner/medial column – the prospective nucleus intermediomedialis.
The outer neuronal column receives its final location laterally and superficially in the intermediate gray matter of the spinal cord and gives rise to the lateral horns of the spinal cord. The inner neuronal column maintains its original position just outside the central canal in front/ventrally of the dorsalis nucleus.
In the fully formed spinal cord the two columns are found at the segment level T1 through L1-2 and in segments S2, S3 and S4.