This means that the arrangement of the components in a particular area of nervous tissue - e.g. the interrelation of the nerve cells in a nucleus, the distribution of cerebral cortex sections in a particular cortex section, the interrelation between the nerve fibers in a conduction pathway - more or less faithfully reflects the appearance of (the organization, the connections of) the body part to which the nervous tissue area relates.

Most talked about in this context is the sensory and motor homunculus. Here, the bark areas that receive and transmit signals from/to the different parts of the opposite half of the body are fairly well cohesive. The body map that can be drawn on each bark area is recognizable, albeit deformed as a result of certain body parts having much greater bark representation than their actual size suggests.

Another example of somatotop organization is found in the cortex of the cerebellum. Additional examples can be found in the front horns of the spinal cord. Here, the motor neuron nuclei that handle the shoulder/hip muscles are located near the midline and those that manage the muscles of the hand and fingers/foot and toes are furthest from the mean line. In addition, the row of flexor muscle nuclei lies within (dorsally about) the row of stretcher muscle nuclei.